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基于印度人群的HL-A 4c复合体分析。

An analysis of the 4c complex of HL-A based on Indian populations.

作者信息

Kostyu D D, Amos D B, Hinostroza S

出版信息

Tissue Antigens. 1975 Jun;5(5):420-30. doi: 10.1111/j.1399-0039.1975.tb01486.x.

Abstract

Sera detecting part or all of the 4c group of HL-A antigenic specificities were compared in two American Indian populations, the Ixils and the Pimas, and in one Spanish-Indian hybrid population, the Mestizos of Peru. Several new variants appeared. These were not identical to HL-A5, W5 or W18. Two of the variants appeared to represent specificities Z57 and Z51 as described during the 1972 Histocompatibility Testing Workshop. In addition, three new specificities could be detected. These were Z42, Ao88 and Ao93. Z42, Ao88 appeared to belong to the 4c complex and Ao93, a new specificity of the second locus, may belong to this same cross-reactive group.

摘要

在两个美洲印第安人群体(伊克希尔人和皮马人)以及一个西班牙 - 印第安混血群体(秘鲁混血儿)中,对检测HL - A抗原特异性4c组部分或全部的血清进行了比较。出现了几个新变体。这些变体与HL - A5、W5或W18并不相同。其中两个变体似乎代表了1972年组织相容性检测研讨会上描述的特异性Z57和Z51。此外,还检测到三种新的特异性。它们是Z42、Ao88和Ao93。Z42、Ao88似乎属于4c复合体,而Ao93是第二个位点的新特异性,可能属于这个相同的交叉反应组。

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