de la Brassinne M, Lachapelle J M
Acta Derm Venereol. 1975;55(3):171-4.
The comparative pattern of 3H-thymidine (3H-T) pulse labelling in lesions of psoriatic erythroderma (3 cases) and of psoriasis vulgaris (20 cases) has been studied by means of radioautography. In the epidermis, no difference was noted between the two types of lesions concerning the epidermal 3H-T labelling index (L.I.) and the localization of labelled cells. The 3H-T L.I. of "round" cells infiltrating the dermis was much higher in lesions of psoriatic erythroderma (4.03 +/- 0.56%) than in lesions of psoriasis vulgaris (0.62 +/- 0.21%), and the difference is highly significant (p less than 0.0001). The findings indicate that most of these labelled cells could well be lymphoblasts, suggesting that an immunological process is possibly involved in the pathogenesis of psoriatic erythroderma.
通过放射自显影术研究了3例红皮病型银屑病和20例寻常型银屑病皮损中3H-胸腺嘧啶核苷（3H-T）脉冲标记的比较模式。在表皮中，两种类型的皮损在表皮3H-T标记指数（L.I.）和标记细胞的定位方面没有差异。浸润真皮的“圆形”细胞的3H-T L.I.在红皮病型银屑病皮损中（4.03±0.56%）比寻常型银屑病皮损中（0.62±0.21%）高得多，差异具有高度显著性（p＜0.0001）。这些发现表明，这些标记细胞中的大多数很可能是成淋巴细胞，提示免疫过程可能参与了红皮病型银屑病的发病机制。
