新型利尿剂美托拉宗的肾排泄
Renal excretion of metolazone, a new diuretic.
作者信息
Belair E J, Cohen A I, Yelnosky J
出版信息
Br J Pharmacol. 1972 Jul;45(3):476-9. doi: 10.1111/j.1476-5381.1972.tb08104.x.
Abstract
- Metolazone, a new diuretic, was found to be excreted by glomerular filtration and renal tubular secretion.2. The secretory mechanism was antagonized by probenecid but this did not affect the diuretic action of metolazone.
摘要
美托拉宗是一种新型利尿剂，经发现它通过肾小球滤过和肾小管分泌排出。
丙磺舒可拮抗这种分泌机制，但这并不影响美托拉宗的利尿作用。
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