无蛋白尿的长期青少年糖尿病患者的肾小球滤过率和肾血浆流量
Glomerular filtration rate and renal plasma flow in long-term juvenile diabetics without proteinuria.
作者信息
Mogensen C E
出版信息
Br Med J. 1972 Nov 4;4(5835):257-9. doi: 10.1136/bmj.4.5835.257.
Abstract
Glomerular filtration rate and renal plasma flow were examined in 16 young male non-proteinuric diabetics (mean age 28.4 years) with a duration of diabetes of over 15 years (mean duration 21.5 years.) In this selected group of long-term diabetics the glomerular filtration rate was clearly increased, the mean being 136 ml/min (+/-S.D. 11.8) (normal value 114 ml/min (+/-14.1), being comparable to that found earlier in short-term diabetics. There was no change in renal plasma flow. It is concluded that kidney function is generally well preserved in long-term diabetics who have not developed proteinuria.
摘要
对16名非蛋白尿性糖尿病男性青年（平均年龄28.4岁）进行了肾小球滤过率和肾血浆流量检查，这些患者糖尿病病程超过15年（平均病程21.5年）。在这群经过挑选的长期糖尿病患者中，肾小球滤过率明显升高，平均值为136毫升/分钟（±标准差11.8）（正常值为114毫升/分钟（±14.1）），与早期发现的短期糖尿病患者的数值相当。肾血浆流量没有变化。得出的结论是，未出现蛋白尿的长期糖尿病患者的肾功能总体上保存良好。
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