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两名恶性高热患者二氧化碳生成增加及其丹曲林控制情况

Increased carbon dioxide production in two patients with malignant hyperpyrexia and its control by dantolene.

作者信息

Liebenschütz F, Mai C, Pickerodt V W

出版信息

Br J Anaesth. 1979 Sep;51(9):899-903. doi: 10.1093/bja/51.9.899.

DOI:10.1093/bja/51.9.899
PMID:508495
Abstract

Two patients with successfully treated malignant hyperpyrexia are reported. Carbon dioxide output, calculated from the respiratory minute volume and PaCO2, was found to be greatly increased in both patients. In the patient who received dantolene 7.5 mg kg-1 the carbon dioxide output decreased rapidly to normal values, whereas in the other patient carbon dioxide output remained increased for several hours.

摘要

报告了两名成功治疗恶性高热的患者。根据每分钟通气量和动脉血二氧化碳分压计算得出的二氧化碳排出量,在这两名患者中均显著增加。在接受7.5毫克/千克丹曲林治疗的患者中,二氧化碳排出量迅速降至正常水平,而在另一名患者中,二氧化碳排出量在数小时内一直升高。

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