正常和银屑病角质形成细胞的质膜研究。I. 材料制备及形态学特征
Studies on the plasma membrane of normal and psoriatic keratinocytes. I. Preparation of material and morphological characterization.
作者信息
Gommans J M, Bergers M, van Erp P E, van den Hurk J J, Mier P D, Roelfzema H
出版信息
Br J Dermatol. 1979 Oct;101(4):407-12. doi: 10.1111/j.1365-2133.1979.tb00018.x.
Abstract
A method is described for the preparation of isolated keratinocytes suitable for subsequent biochemical studies. Scanning electron microscopy showed that the maturation process is accompanied by an increase in cell size and a shortening and eventual loss of microvilli. Psoriatic keratinocytes are distinguishable by exhibiting longer microvilli at all levels of maturation.
摘要
本文描述了一种制备适合后续生化研究的分离角质形成细胞的方法。扫描电子显微镜显示，成熟过程伴随着细胞大小的增加以及微绒毛的缩短和最终消失。银屑病角质形成细胞在所有成熟阶段均表现出较长的微绒毛，以此可加以区分。
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