Illei G, Morgan D M
Br J Obstet Gynaecol. 1979 Nov;86(11):873-7. doi: 10.1111/j.1471-0528.1979.tb10714.x.
Polyamine oxidase activity was measured in different compartments of the feto-maternal unit by a radiochemical method. The activity in the retroplacental serum (mainly of intervillous origin) was 20 to 30 times higher than in maternal uterine or peripheral venous blood sera. No activity was found in the fetal cord blood sera. The enzyme level in the maternal peripheral sera fell to undetectable levels within 72 hours post partum. Preliminary data indicate that the enzyme might be produced by the decidua rather than by the placenta. It is suggested that the enzyme may constitute an important part of a supposed local immunological barrier formed at the placental bed to help to protect the fetal allograft from maternal immune rejection through a local suppressive effect on maternal cellular immunity.
采用放射化学方法测定了母胎单位不同部位的多胺氧化酶活性。胎盘后血清（主要来自绒毛间隙）中的活性比母体子宫或外周静脉血血清中的活性高20至30倍。在胎儿脐带血血清中未发现活性。产后72小时内，母体外周血清中的酶水平降至无法检测的水平。初步数据表明，该酶可能由蜕膜而非胎盘产生。有人提出，该酶可能是胎盘床形成的假定局部免疫屏障的重要组成部分，通过对母体细胞免疫的局部抑制作用，帮助保护胎儿同种异体移植物免受母体免疫排斥。
