Wagner G C, Seiden L S, Schuster C R
Drug Alcohol Depend. 1979 Sep;4(5):435-8. doi: 10.1016/0376-8716(79)90076-0.
Repeated administration of methamphetamine was found to cause long-term changes in caudate dopamine levels in the rat and guinea pig. Methamphetamine was administered twice a day for thirty days. Two weeks following the last injection, the animals were killed and brains assayed for catecholamine content. These long-term depletions of dopamine, when combined with similar observations previously reported in rhesus monkeys, indicate a species generality of the effects of methamphetamine on caudate dopamine levels.
