小鼠被动血清病：血管活性胺在免疫复合物肾小球沉积中的作用。
Passive serum sickness in the mouse: the role of vasoactive amines in glomerular deposition of immune complexes.
作者信息
Ford P M
出版信息
Br J Exp Pathol. 1976 Apr;57(2):148-51.
Abstract
This paper reports a study of the importance of vasoactive amines in glomerular localization of passively administered immune complexes in the mouse. Two strains of mice were investigated, one sensitive and the other relatively resistant to the anaphylactogenic effect of intravenously administered immune complexes. The effect on glomerular deposition immune complexes in animals of both strains treated with either vasoactive amine depletors or antagonists leads to the conclusion that in this experimental system vasoactive amines do not play a major part in the glomerular localization of immune complexes.
摘要
本文报道了一项关于血管活性胺在小鼠被动给予免疫复合物的肾小球定位中的重要性的研究。研究了两种品系的小鼠，一种对静脉注射免疫复合物的过敏反应敏感，另一种相对耐受。用血管活性胺耗竭剂或拮抗剂处理这两种品系动物后，对肾小球沉积免疫复合物的影响得出结论：在这个实验系统中，血管活性胺在免疫复合物的肾小球定位中不起主要作用。
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本文引用的文献
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Br J Pharmacol Chemother. 1963 Jun;20(3):389-98. doi: 10.1111/j.1476-5381.1963.tb01477.x.
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Passive serum sickness in the mouse: effect of interstrain differences on glomerular deposition of immune complexes.小鼠被动血清病：品系间差异对免疫复合物肾小球沉积的影响。
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