紫外线照射的中国仓鼠细胞中的脱氧核糖核酸合成
Deoxyribonucleic acid synthesis in ultraviolet-light-irradiated Chinese hamster cells.
作者信息
Meyn R E, Humphrey R M
出版信息
Biophys J. 1971 Mar;11(3):295-301. doi: 10.1016/S0006-3495(71)86215-X.
Abstract
Two mammalian cell lines, Chinese hamster ovary (CHO) which can recover colony-forming ability between fractionated doses of ultraviolet light (UV), and Chinese hamster B-14FAF28 which cannot recover, were tested for the ability to bypass UV-induced photoproducts in DNA during postirradiation DNA synthesis. The molecular weight distributions of newly synthesized DNA in UV-irradiated populations of both cell lines showed evidence for photoproduct bypass. Hence, the bypass mechanism does not correlate with recovery after UV.
摘要
两种哺乳动物细胞系，即能够在紫外线（UV）分次照射剂量之间恢复集落形成能力的中国仓鼠卵巢（CHO）细胞系和不能恢复的中国仓鼠B - 14FAF28细胞系，被测试了在照射后DNA合成过程中绕过DNA中UV诱导光产物的能力。两种细胞系经UV照射群体中新合成DNA的分子量分布均显示有光产物绕过的证据。因此，绕过机制与UV照射后的恢复无关。
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本文引用的文献
1
THE INDUCTION OF THYMINE DIMERS IN ULTRAVIOLET-IRRADIATED MAMMALIAN CELLS.紫外线照射哺乳动物细胞时胸腺嘧啶二聚体的诱导形成
Radiat Res. 1965 Apr;24:667-72.
2
EVIDENCE FOR REPAIR-REPLICATION OF ULTRAVIOLET DAMAGED DNA IN BACTERIA.细菌中紫外线损伤DNA修复复制的证据
J Mol Biol. 1964 Aug;9:395-410. doi: 10.1016/s0022-2836(64)80216-3.
3
RELEASE OF ULTRAVIOLET LIGHT-INDUCED THYMINE DIMERS FROM DNA IN E. COLI K-12.大肠杆菌K-12中DNA上紫外线诱导胸腺嘧啶二聚体的释放
Proc Natl Acad Sci U S A. 1964 Feb;51(2):293-300. doi: 10.1073/pnas.51.2.293.
4
THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM.胸腺嘧啶二聚体从DNA中的消失：一种纠错机制。
Proc Natl Acad Sci U S A. 1964 Feb;51(2):226-31. doi: 10.1073/pnas.51.2.226.
5
Relative ultraviolet sensitivity of different phases in the cell cycle of Chinese hamster cells grown in vitro.
Radiat Res. 1963 Jun;19:247-60.
6
Characterization of macromolecules by constant velocity sedimentation.通过等速沉降法对大分子进行表征。
Nature. 1967 Jul 22;215(5099):360-3. doi: 10.1038/215360a0.
7
Evidence for dark-reactivation of ultraviolet light damage in mouse L cells.小鼠L细胞中紫外线损伤暗修复的证据。
Radiat Res. 1967 May;31(1):121-38.
8
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9
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Repair replication, unscheduled DNA synthesis, and the repair of mammalian DNA.修复复制、非常规DNA合成与哺乳动物DNA修复
Radiat Res. 1969 Mar;37(3):451-66.
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