Watney P J, Chance G W, Scott P, Thompson J M
Br Med J. 1971 May 22;2(5759):432-6. doi: 10.1136/bmj.2.5759.432.
To assess the significance of various maternal and neonatal factors in the aetiology of neonatal tetany we have investigated the serum calcium, phosphorus, magnesium, and heat-labile alkaline phosphatase of 250 mothers from three ethnic groups at several stages of pregnancy and the serum calcium, phosphorus, and magnesium of many of their infants. Subclinical hypocalcaemia was found to be much commoner in full-term infants on the sixth day of life than is generally appreciated, especially during the winter months and in babies of Asian parents. It is considered that this is a result of high phosphorus loads in artificial milks and is also influenced by maternal vitamin D and possibly calcium intake during pregnancy. The importance of ensuring that Asian women take adequate vitamin D supplements during pregnancy is stressed.
为评估各种孕产妇和新生儿因素在新生儿手足搐搦病因学中的意义,我们调查了来自三个种族群体的250名母亲在妊娠几个阶段的血清钙、磷、镁和热不稳定碱性磷酸酶,以及她们许多婴儿的血清钙、磷和镁。结果发现,足月婴儿出生后第六天的亚临床低钙血症比一般认为的更为常见,尤其是在冬季以及亚洲父母的婴儿中。据认为,这是人工喂养奶粉中磷含量过高的结果,并且还受到孕期母亲维生素D以及可能的钙摄入量的影响。强调了确保亚洲女性在孕期摄入足够维生素D补充剂的重要性。