Ford J A, McIntosh W V, Butterfield R, Preece M A, Pietrek J, Arrowsmith W A, Arthurton M W, Turner W, O'Riordan J L, Dunnigan M G
Arch Dis Child. 1976 Dec;51(12):939-43. doi: 10.1136/adc.51.12.939.
A survey of the vitamin D status of Bradford schoolchildren was carried out in April 1973, employing conventional biochemistry, radiology, and measurement of 25-hydroxycholecalciferol levels. Biochemical evidence of rickets was present in 45% of the Asians. When re-examined in September, several children showed spontaneous biochemical resolution; nevertheless, radiological abnormalities were present in 12% of the original sample. No evidence of rickets was detected in the smaller White sample. Minor biochemical abnormalities were present in 9 of the 40 West Indian children. A study of admissions of Bradford hospitals in the 4 years 1969-1972 inclusive confirmed that clinical vitamin D deficiency was confined to Asians except for a few cases of infantile rickets in White children. The probability that one Asian child in 40 may require admission during the period from birth to adolescence emphasizes the urgent need for the introduction of prophylactic measures.
1973年4月对布拉德福德市学童的维生素D状况进行了一项调查，采用了传统的生化、放射学方法以及对25-羟胆钙化醇水平的测量。45%的亚洲儿童有佝偻病的生化证据。9月再次检查时，一些儿童出现了自发的生化指标恢复正常；然而，在最初样本中有12%的儿童存在放射学异常。在较小的白人样本中未检测到佝偻病证据。40名西印度儿童中有9名存在轻微生化异常。对1969年至1972年这四年间布拉德福德市医院的入院情况研究证实，临床维生素D缺乏症仅限于亚洲儿童，白人儿童仅有少数婴儿佝偻病病例。40名亚洲儿童中就有1名在从出生到青春期期间可能需要住院，这一概率凸显了采取预防措施的迫切需求。
