Methylation of mu2 bacteriophage ribonucleic acid by the carcinogen N-methyl-N-nitrosourea: evidence for O-methylation.
作者信息
Lawley P D, Shooter K V, House W L, Shah S A
出版信息
Biochem J. 1971 Mar;122(1):22P. doi: 10.1042/bj1220022pb.
Abstract
摘要
相似文献
1
Methylation of mu2 bacteriophage ribonucleic acid by the carcinogen N-methyl-N-nitrosourea: evidence for O-methylation.致癌物质N-甲基-N-亚硝基脲对μ2噬菌体核糖核酸的甲基化作用：O-甲基化的证据。
Biochem J. 1971 Mar;122(1):22P. doi: 10.1042/bj1220022pb.
2
Methylation of ribonucleic acid by the carcinogens dimethyl sulphate, N-methyl-N-nitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine. Comparisons of chemical analyses at the nucleoside and base levels.致癌物质硫酸二甲酯、N-甲基-N-亚硝基脲和N-甲基-N'-硝基-N-亚硝基胍对核糖核酸的甲基化作用。核苷和碱基水平化学分析的比较。
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Reaction of alkylating mutagens and carcinogens with nucleic acids: N-3 of guanine as a site of alkylation by N-methyl-N-nitrosourea and dimethyl sulphate.烷基化诱变剂和致癌物与核酸的反应：鸟嘌呤的N-3作为被N-甲基-N-亚硝基脲和硫酸二甲酯烷基化的位点。
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The molecular basis for biological inactivation of nucleic acids. The action of methylating agents on the ribonucleic acid-containing bacteriophage R17.核酸生物失活的分子基础。甲基化试剂对含核糖核酸的噬菌体R17的作用。
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[Distribution of N-( 14 C) methyl-N-nitrosourea in the rat after its systemic administration].[全身给药后N-(14C)甲基-N-亚硝基脲在大鼠体内的分布]
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Tissue-dependent differences in DNA methylation products of mice treated with methyl-labelled methylnitrosourea.用甲基标记的甲基亚硝基脲处理的小鼠DNA甲基化产物的组织依赖性差异。
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Chemical modification of viral ribonucleic acid. 8. The chemical and biological effects of methylating agents and nitrosoguanidine on tobacco mosaic virus.病毒核糖核酸的化学修饰。8. 甲基化剂和亚硝基胍对烟草花叶病毒的化学及生物学效应。
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Alkylation of rat brain nucleic acids by N-methyl-N-nitrosourea and methyl methanesulphonate.N-甲基-N-亚硝基脲和甲磺酸甲酯对大鼠脑核酸的烷基化作用。
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Nitrosamine-induced carcinogenesis. The alklylation of nucleic acids of the rat by N-methyl-N-nitrosourea, dimethylnitrosamine, dimethyl sulphate and methyl methanesulphonate.亚硝胺诱导的致癌作用。N-甲基-N-亚硝基脲、二甲基亚硝胺、硫酸二甲酯和甲磺酸甲酯对大鼠核酸的烷基化作用。
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本文引用的文献
1
Possible relevance of O-6 alkylation of deoxyguanosine to the mutagenicity and carcinogenicity of nitrosamines and nitrosamides.脱氧鸟苷的O-6烷基化与亚硝胺和亚硝酰胺的致突变性和致癌性之间可能存在的关联。
Nature. 1969 Jul 12;223(5202):206-7. doi: 10.1038/223206a0.
2
A possible mechanism of inhibition of protein synthesis by dimethylnitrosamine.二甲基亚硝胺抑制蛋白质合成的一种可能机制。
Biochem J. 1967 Nov;105(2):625-31. doi: 10.1042/bj1050625.
3
Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N'-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation.N-甲基-N'-硝基-N-亚硝基胍对培养的哺乳动物细胞中脱氧核糖核酸的甲基化作用。细胞内硫醇浓度对甲基化程度的影响以及鸟嘌呤的6-氧原子作为甲基化位点的情况。
Biochem J. 1970 Feb;116(4):693-707. doi: 10.1042/bj1160693.
4
Rapid separation of nucleosides and nucleotides by cation-exchange column chromatography.通过阳离子交换柱色谱法快速分离核苷和核苷酸。
J Chromatogr. 1969 Oct 28;44(2):342-8. doi: 10.1016/s0021-9673(01)92545-2.
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