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Alkylation of rat brain nucleic acids by N-methyl-N-nitrosourea and methyl methanesulphonate.

作者信息

Kleihues P, Magee P N

出版信息

J Neurochem. 1973 Feb;20(2):595-606. doi: 10.1111/j.1471-4159.1973.tb12158.x.

DOI:10.1111/j.1471-4159.1973.tb12158.x
PMID:4698302
Abstract
摘要

相似文献

1
Alkylation of rat brain nucleic acids by N-methyl-N-nitrosourea and methyl methanesulphonate.N-甲基-N-亚硝基脲和甲磺酸甲酯对大鼠脑核酸的烷基化作用。
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3
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Reaction of methyl methanesulphonate with nucleic acids of fetal and newborn rats in vivo.甲磺酸甲酯与新生大鼠和胎鼠核酸在体内的反应。
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Methylation in vivo of guanine in the nucleic acids of rat testes by methyl methane sulphonate.甲基磺酸甲酯对大鼠睾丸核酸中鸟嘌呤的体内甲基化作用。
Nature. 1967 May 27;214(5091):918-9. doi: 10.1038/214918a0.
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Alkylation of porcine nucleic acids following intravenous and intragastric application of n-methyl-n-nitrosourea.
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7
Methylation of nuclear proteins by dimethylnitrosamine and by methionine in the rat in vivo.大鼠体内二甲基亚硝胺和蛋氨酸对核蛋白的甲基化作用。
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Methylation of rat-liver RNA in vivo by methyl methanesulphonate.用甲磺酸甲酯对大鼠肝脏RNA进行体内甲基化。
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Carcinogenicity of N-methyl-N-nitrosourea: possible role of excision repair of O6-methylguanine from DNA.N-甲基-N-亚硝基脲的致癌性：DNA中O6-甲基鸟嘌呤切除修复的可能作用。
J Natl Cancer Inst. 1974 Dec;53(6):1839-41.

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2
Significance of experimental models in neurooncology.
Neurosurg Rev. 1980;3(2):129-37. doi: 10.1007/BF01644065.
3
Inhibition of protein synthesis by N-methyl-N-nitrosourea in vivo.体内N-甲基-N-亚硝基脲对蛋白质合成的抑制作用。
Biochem J. 1973 Oct;136(2):303-9. doi: 10.1042/bj1360303.
4
Persistence of O6-ethylguanine in rat-brain DNA: correlation with nervous system-specific carcinogenesis by ethylnitrosourea.大鼠脑DNA中O6-乙基鸟嘌呤的持久性：与乙基亚硝基脲诱导的神经系统特异性致癌作用的相关性。
Proc Natl Acad Sci U S A. 1974 Mar;71(3):639-43. doi: 10.1073/pnas.71.3.639.
5
Reaction of methyl methanesulphonate with nucleic acids of fetal and newborn rats in vivo.甲磺酸甲酯与新生大鼠和胎鼠核酸在体内的反应。
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1974;81(3-4):273-83. doi: 10.1007/BF00305030.
6
Molecular and cellular mechanisms associated with pulse-carcinogenesis in the rat nerbous system by ethyinitrosourea: ethylation of nucleic acids and elimination rates of ethylated bases from the DNA of different tissues.乙基亚硝基脲诱导大鼠神经系统脉冲致癌作用的分子和细胞机制：核酸的乙基化及不同组织DNA中乙基化碱基的消除速率
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1974;82(1):37-64. doi: 10.1007/BF00304382.
7
Alkylation of porcine nucleic acids following intravenous and intragastric application of n-methyl-n-nitrosourea.
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1973 Dec 28;80(4):317-22. doi: 10.1007/BF00284367.
8
DNA methylation in the digestive tract of F344 rats during chronic exposure to N-methyl-N-nitrosourea.F344大鼠长期暴露于N-甲基-N-亚硝基脲期间消化道中的DNA甲基化
J Cancer Res Clin Oncol. 1991;117(1):13-8. doi: 10.1007/BF01613190.
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Chemical carcinogenesis in the nervous system. Preferential accumulation of O6-methylguanine in rat brain deoxyribonucleic acid during repetitive administration of N-methyl-N-nitrosourea.神经系统中的化学致癌作用。重复给予N-甲基-N-亚硝基脲期间大鼠脑脱氧核糖核酸中O6-甲基鸟嘌呤的优先积累。
Biochem J. 1975 Jun;148(3):521-5. doi: 10.1042/bj1480521.
10
Methylated purines in the deoxyribonucleic acid of various Syrian-golden-hamster tissues after administration of a hepatocarcinogenic dose of dimethylnitrosamine.给予致癌剂量的二甲基亚硝胺后，叙利亚金仓鼠各种组织的脱氧核糖核酸中的甲基化嘌呤。
Biochem J. 1976 Sep 1;157(3):627-34. doi: 10.1042/bj1570627.