Larsen N A, Pakkenberg H, Damsgaard E, Heydorn K
J Neurol Sci. 1979 Aug;42(3):407-16. doi: 10.1016/0022-510x(79)90173-4.
The concentrations of arsenic, manganese and selenium per gram wet tissue weight were determined in samples from 24 areas of normal human brain from 5 persons with ages ranging from 15 to 81 years of age. The concentrations of the 3 elements were determined for each sample by means of neutron activation analysis with radiochemical separation. Distinct patterns of distribution were shown for each of the 3 elements. Variations between individuals were found for some but not all brain areas, resulting in coefficients of variation between individuals of about 30% for arsenic, 10% for manganese and 20% for selenium. The results seem to indicate that arsenic is associated with the lipid phase, manganese with the dry matter and selenium with the aqueous phase of brain tissue.
对5名年龄在15至81岁之间的人的24个正常人类脑区样本，测定了每克湿组织重量中砷、锰和硒的浓度。通过放射化学分离的中子活化分析法测定了每个样本中这3种元素的浓度。这3种元素各自呈现出不同的分布模式。在部分而非全部脑区发现了个体间的差异，导致砷的个体间变异系数约为30%，锰为10%，硒为20%。结果似乎表明，砷与脂质相相关，锰与干物质相关，而硒与脑组织的水相相关。
