原子分辨率下左手双螺旋DNA片段的分子结构。
Molecular structure of a left-handed double helical DNA fragment at atomic resolution.
作者信息
Wang A H, Quigley G J, Kolpak F J, Crawford J L, van Boom J H, van der Marel G, Rich A
出版信息
Nature. 1979 Dec 13;282(5740):680-6. doi: 10.1038/282680a0.
DOI:10.1038/282680a0
PMID:514347
Abstract
The DNA fragment d(CpGpCpGpCpG) crystallises as a left-handed double helical molecule with Watson-Crick base pairs and an antiparallel organisation of the sugar phosphate chains. The helix has two nucleotides in the asymmetric unit and contains twelve base pairs per turn. It differs significantly from right-handed B-DNA.
摘要
DNA片段d（CpGpCpGpCpG）以左手双螺旋分子形式结晶，具有沃森-克里克碱基对和糖磷酸链的反平行排列。该螺旋在不对称单元中有两个核苷酸，每圈包含十二个碱基对。它与右手B-DNA有显著差异。
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