3,5-二叔丁基苯基N-甲基氨基甲酸酯在昆虫体内及小鼠肝脏酶作用下的代谢
The metabolism of 3,5-di-tert.-butylphenyl N-methylcarbamate in insects and by mouse liver enzymes.
作者信息
Douch P G, Smith J N
出版信息
Biochem J. 1971 Nov;125(2):395-400. doi: 10.1042/bj1250395.
Abstract
The oxidation of 3,5-di-tert.-butylphenyl N-methylcarbamate (Butacarb) has been studied in the flies Musca domestica and Lucilia sericata, grass grubs Costelytra zealandica and the mouse. In all species eleven oxidation products, which were formed by hydroxylation of the tert.-butyl groups and the N-methyl group, were detected.
摘要
已在家蝇、丝光绿蝇、新西兰肋翅鳃角金龟和小鼠中研究了3,5-二叔丁基苯基N-甲基氨基甲酸酯（丁卡威）的氧化作用。在所有物种中，均检测到了11种氧化产物，这些产物是由叔丁基和N-甲基的羟基化形成的。
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本文引用的文献
1
The metabolism of 3:5-di-tert.-butyl-4-hydroxytoluene and 3:5-di-tert.-butyl-4-hydroxybenzoic acid in the rabbit.3:5-二叔丁基-4-羟基甲苯和3:5-二叔丁基-4-羟基苯甲酸在兔体内的代谢
Biochem J. 1961 Apr;78(4):758-66. doi: 10.1042/bj0780758.
2
Studies in detoxication. 60. The metabolism of alkylbenzenes: isopropylbenzene (cumene) and derivatives of hydratropic acid.解毒作用的研究。60. 烷基苯的代谢：异丙基苯（枯烯）和氢化阿托酸的衍生物。
Biochem J. 1955 Jan;59(1):153-9. doi: 10.1042/bj0590153.
3
Oxidation of methyl groups by grass grubs and vertebrate liver enzymes.草地蛴螬和脊椎动物肝脏酶对甲基的氧化作用。
Biochem J. 1967 Feb;102(2):504-10. doi: 10.1042/bj1020504.
4
Enzymic oxidation of some alkylbenzenes in insects and vertebrates.昆虫和脊椎动物中某些烷基苯的酶促氧化作用。
Biochem J. 1967 Feb;102(2):498-503. doi: 10.1042/bj1020498.
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Food Cosmet Toxicol. 1967 Oct;5(4):475-9. doi: 10.1016/s0015-6264(67)83148-1.
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Biochem J. 1970 Jun;118(1):1-8. doi: 10.1042/bj1180001.
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J Pharm Pharmacol. 1970 May;22(5):375-6. doi: 10.1111/j.2042-7158.1970.tb08541.x.
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