病毒基因组的整合
Integration of viral genomes.
作者信息
Zhdanov V M
出版信息
Nature. 1975 Aug 7;256(5517):471-3. doi: 10.1038/256471a0.
DOI:10.1038/256471a0
PMID:51475
Abstract
DNA transcripts of infectious RNA viruses were found to be integrated in the DNA of chronically-infected tissue cultures. DNA sequences homologous to RNA of measles virus were found in tissues affected with systemic lupus erythemotosus. These data open up a new class of virus-cell interaction that may be a result of cooperation between infectious and oncogenic viruses.
摘要
在长期感染的组织培养物的DNA中发现了传染性RNA病毒的DNA转录本。在患有系统性红斑狼疮的组织中发现了与麻疹病毒RNA同源的DNA序列。这些数据揭示了一种新的病毒-细胞相互作用类型，这可能是传染性病毒和致癌病毒之间合作的结果。
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