Currie R A, Kadis V W, Breitkreitz W E, Cunningham G B, Bruns G W
Pestic Monit J. 1979 Sep;13(2):52-5.
Organochlorine pesticide residues were determined in human milk of residents of Alberta, Canada, during 1966-70 and 1977-78. Levels of polybrominated biphenyls (PBBs), polychlorinated biphenyls (PCBs), and some common organophosphorus pesticides were also monitored during 1977-78. Average residue levels were generally lower in 1977-78 samples, whereas the percent incidence of residues was generally lower in 1966-70 samples. beta-BHC was found in all 1977-78 samples, but was not detected in 1966-70 samples. PCBs were detected in all but two of the 1977-78 samples. Average levels of p,p'-DDT and is metabolites were substantially lower during the second period than during the first. Large increases in the average levels and percent incidences of heptachlor epoxide and o,p'-DDT have been attributed to refinements in both cleanup and gas chromatographic analysis. Although no PBBs or organophosphorus pesticides were detected in 1977-78 samples, an unidentified hydrocarbon similar to dicofol was found in all samples of that period. No correlation between donor age groups and average pesticide residue levels could be inferred.
1966 - 1970年以及1977 - 1978年期间,对加拿大艾伯塔省居民的母乳中的有机氯农药残留进行了测定。1977 - 1978年期间还监测了多溴联苯(PBBs)、多氯联苯(PCBs)以及一些常见有机磷农药的含量。1977 - 1978年样本中的平均残留水平总体较低,而1966 - 1970年样本中残留的发生率总体较低。在1977 - 1978年的所有样本中均发现了β - 六六六,但在1966 - 1970年样本中未检测到。在1977 - 1978年的样本中,除两个样本外均检测到了多氯联苯。第二阶段p,p'-滴滴涕及其代谢物的平均水平显著低于第一阶段。七氯环氧化物和o,p'-滴滴涕的平均水平及发生率大幅上升归因于净化和气相色谱分析技术的改进。尽管在1977 - 1978年的样本中未检测到多溴联苯或有机磷农药,但在该时期的所有样本中都发现了一种类似于三氯杀螨醇的不明碳氢化合物。无法推断出供体年龄组与平均农药残留水平之间存在相关性。