Sergysels R, De Coster A, Degre S, Denolin H
Respiration. 1979;38(2):105-11. doi: 10.1159/000194066.
20 patients suffering from chronic obstructive lung disease (COLD) were submitted to a 6-month rehabilitation program including breathing exercises only (A) or coupled with bicycle training (B). Functional results obtained at rest were the following: for A: nonsignificant changes in FRC, RV, FEV1, Raw, Pa O2, pH, Pp, VO2 max SL but significant changes (p less than 0.05)for TLC (+ 214 cm3), VC (+ 171 cm3), DL CO (+ 1.79 ml), Pa CO2 (-2.9 mm Hg). For B: similar changes as for A with additional significant changes in PaO2 (+ 7.4 mm Hg) VO2 max SL (+ 250 ml) and Pp (-4 mm Hg). These results, although minimal, are attributed to improved respiratory muscle strength and improved alveolar ventilation. Exercise training adds an increased ability to sustain higher loads.
20名慢性阻塞性肺疾病（COLD）患者接受了为期6个月的康复计划，其中包括仅进行呼吸练习（A组）或结合自行车训练（B组）。静息时获得的功能结果如下：对于A组：功能残气量（FRC）、残气量（RV）、第一秒用力呼气容积（FEV1）、气道阻力（Raw）、动脉血氧分压（Pa O2）、pH值、肺动脉压（Pp）、最大摄氧量（VO2 max SL）无显著变化，但肺总量（TLC）增加214立方厘米、肺活量（VC）增加171立方厘米、一氧化碳弥散量（DL CO）增加1.79毫升、动脉血二氧化碳分压（Pa CO2）降低2.9毫米汞柱有显著变化（p小于0.05）。对于B组：与A组有类似变化，另外动脉血氧分压增加7.4毫米汞柱、最大摄氧量增加250毫升和肺动脉压降低4毫米汞柱有显著变化。这些结果虽然微小，但归因于呼吸肌力量的改善和肺泡通气的改善。运动训练增加了承受更高负荷的能力。
