Cockcroft A E, Saunders M J, Berry G
Thorax. 1981 Mar;36(3):200-3. doi: 10.1136/thx.36.3.200.
A randomised controlled study of the effects of exercise training in 39 patients with chronic respiratory disability was performed. Exercise training began with six weeks in a rehabilitation centre and was continued at home. The original control group attended the rehabilitation centre after the controlled part of the study. The treated group experienced subjective benefit from rehabilitation. The 12-minute walking distance increased on average from 523 m to 643 m in the treatment group and from 564 m to 607 m in the control group. The treatment effect of 77 m (SE 33 m) was significant at the 5% level. Treadmill exercise performance changed little and resting lung function was unaltered after rehabilitation. The treatment group maintained most of their improvement seven months later and the original control subjects improved after their rehabilitation. The study confirms the beneficial effects of exercise training in the chronically breathless and it suggests that the 12-minute walking distance is a useful index of changes in everyday exercise tolerance.
对39例慢性呼吸功能障碍患者进行了运动训练效果的随机对照研究。运动训练始于在康复中心进行的为期六周的训练，并在家中继续进行。原始对照组在研究的对照部分结束后进入康复中心。治疗组从康复中获得了主观益处。治疗组的12分钟步行距离平均从523米增加到643米，对照组从564米增加到607米。77米（标准误33米）的治疗效果在5%水平上具有显著性。康复后跑步机运动表现变化不大，静息肺功能未改变。治疗组在七个月后仍保持了大部分改善，而原始对照组在康复后也有所改善。该研究证实了运动训练对慢性气喘患者的有益效果，并表明12分钟步行距离是日常运动耐力变化的一个有用指标。
