Owen D A
Br J Pharmacol. 1971 Nov;43(3):668-70. doi: 10.1111/j.1476-5381.1971.tb07196.x.
The blood pressure responses to intravenous injections of noradrenaline, tyramine and McN-A-343 have been determined in conscious cats and in cats under pentobarbitone sodium, alpha-chloralose, urethane or alpha-chloralose plus urethane anaesthesia. All four anaesthetic agents reduced the pressor responses, the reduction being most pronounced with urethane and least pronounced with alpha-chloralose. Pentobarbitone sodium exerted a greater inhibitory effect on the responses to McN-A-343 than on those to noradrenaline or tyramine.
已测定了清醒猫以及处于戊巴比妥钠、α-氯醛糖、乌拉坦或α-氯醛糖加乌拉坦麻醉状态下的猫对静脉注射去甲肾上腺素、酪胺和 McN - A - 343 的血压反应。所有这四种麻醉剂均降低了升压反应,其中乌拉坦导致的降低最为显著,而α-氯醛糖导致的降低最不明显。戊巴比妥钠对 McN - A - 343 反应的抑制作用比对去甲肾上腺素或酪胺反应的抑制作用更大。