Jamieson M P, Walbaum P R, McCormack R J
Thorax. 1979 Oct;34(5):612-5. doi: 10.1136/thx.34.5.612.
In a 20-year period (1958-77) 43 patients underwent combined pulmonary and chest wall resection for bronchial carcinoma with local invasion of the thoracic wall. The clinical data, symptoms, surgical procedures, pathology, and results are reviewed. Pain was the usual presenting symptom. The operative mortality was 16%, respiratory complications causing most of the postoperative morbidity and mortality. These complications were less common after pneumonectomy. Long-term survival was achieved in only three cases with a corrected three-year survival rate of 10%. The survivors had certain pathological and operative features in common that may have prognostic significance. Recurrent carcinoma was responsible for most late deaths. Despite the poor overall prognosis, surgical management provided reasonable palliation and occasionally resulted in prolonged disease-free survival.
在20年期间(1958 - 1977年),43例因支气管癌侵犯胸壁而接受肺和胸壁联合切除术的患者。对其临床资料、症状、手术方式、病理及结果进行回顾。疼痛是常见的首发症状。手术死亡率为16%,呼吸并发症是术后发病和死亡的主要原因。这些并发症在肺切除术后较少见。仅3例患者获得长期生存,校正三年生存率为10%。幸存者有某些共同的病理和手术特征,可能具有预后意义。复发性癌是大多数晚期死亡的原因。尽管总体预后较差,但手术治疗提供了合理的姑息治疗,偶尔可导致无病生存期延长。