• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Irreversible enzyme inhibitors. 185. Active-site-directed irreversible inhibitors of guanine deaminase derived from 9-phenylguanine bearing a terminal sulfonyl fluoride. 2.

作者信息

Baker B R, Siebenneick H U

出版信息

J Med Chem. 1971 Sep;14(9):802-5. doi: 10.1021/jm00291a006.

DOI:10.1021/jm00291a006
PMID:5168672
Abstract
摘要

相似文献

1
Irreversible enzyme inhibitors. 185. Active-site-directed irreversible inhibitors of guanine deaminase derived from 9-phenylguanine bearing a terminal sulfonyl fluoride. 2.不可逆酶抑制剂。185. 源自带有末端磺酰氟的9-苯基鸟嘌呤的鸟嘌呤脱氨酶的活性位点导向不可逆抑制剂。2.
J Med Chem. 1971 Sep;14(9):802-5. doi: 10.1021/jm00291a006.
2
Irreversible enzyme inhibitors. 148. Active-site-directed irreversible inhibitors of guanine deaminase derived from 9-phenylguanine bearing a terminal sulfonyl fluoride.不可逆酶抑制剂。148. 源自带有末端磺酰氟的9-苯基鸟嘌呤的鸟嘌呤脱氨酶的活性位点导向不可逆抑制剂。
J Med Chem. 1969 Mar;12(2):216-20. doi: 10.1021/jm00302a005.
3
Irreversible enzyme inhibitors. 184. An affinity column for purification of rat liver guanine deaminase and xanthine oxidase.不可逆酶抑制剂。184. 一种用于纯化大鼠肝脏鸟嘌呤脱氨酶和黄嘌呤氧化酶的亲和柱。
J Med Chem. 1971 Sep;14(9):799-801. doi: 10.1021/jm00291a005.
4
Irreversible enzyme inhibitors. 186. Irreversible inhibitors of the C'la component of complement derived from m-(phenoxypropoxy)benzamidine by bridging to a terminal sulfonyl fluoride.不可逆酶抑制剂。186. 通过与末端磺酰氟连接从间（苯氧基丙氧基）苯甲脒衍生而来的补体C'la成分的不可逆抑制剂。
J Med Chem. 1971 Sep;14(9):805-8. doi: 10.1021/jm00291a007.
5
Irreversible enzyme inhibitors. CXII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-phenyl-s-triazine substituted with a terminal sulfonyl fluoride. II.不可逆酶抑制剂。CXII。源自4,6-二氨基-1,2-二氢-2,2-二甲基-1-苯基-s-三嗪并被末端磺酰氟取代的二氢叶酸还原酶的活性位点导向不可逆抑制剂。II。
J Med Chem. 1968 Jan;11(1):38-41. doi: 10.1021/jm00307a007.
6
Irreversible enzyme inhibitors. CXIX. Active-site-directed irreversible inhibitors of dihydrofolic reductase with tissue specificity derived from 2,4,6-triaminopyrimidine with a terminal sulfonyl fluoride at the 5 position.不可逆酶抑制剂。CXIX。具有组织特异性的二氢叶酸还原酶活性位点导向不可逆抑制剂，其衍生自5位带有末端磺酰氟的2,4,6 - 三氨基嘧啶。
J Med Chem. 1968 May;11(3):489-94. doi: 10.1021/jm00309a018.
7
Irreversible enzyme inhibitors. CXXXVII. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-(p-aminomethylphenoxymethyl)-2,4-diamino-5-(3,4-dichlorophenyl)pyrimidine bearing a terminal sulfonyl fluoride.
J Med Chem. 1969 Jan;12(1):86-8. doi: 10.1021/jm00301a022.
8
Irreversible enzyme inhibitors. CXXXIX. p-(4,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)phenylpropionylsulfanilyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase. VI. Further studies on effects of substitution on the propionamide bridge on isozyme specificity.
J Med Chem. 1969 Jan;12(1):92-4. doi: 10.1021/jm00301a024.
9
Irreversible enzyme inhibitors. 138. Active-site-directed irreversible inhibitors of dihydrofolic reductase derived from 6-(p-aminomethylphenethyl)-- 2,4-diamino-5-(3,4-dichlorophenyl)pyrimidine with a terminal sulfonyl fluoride.
J Med Chem. 1969 Jan;12(1):89-91. doi: 10.1021/jm00301a023.
10
Irreversible enzyme inhibitors. CXLIV. Proteolytic enzymes. VII. Additonal active-site-directed irreversible inhibitors of trypsin derived from m- and p-(phenoxyalkoxy)benzamidines with a terminal sulfonyl fluoride.
J Med Chem. 1969 Jan;12(1):112-7. doi: 10.1021/jm00301a029.

引用本文的文献

1
Structure-based design and analysis of SuFEx chemical probes.基于结构的硫氟交换（SuFEx）化学探针的设计与分析
RSC Med Chem. 2020 Jan 6;11(1):10-17. doi: 10.1039/c9md00542k. eCollection 2020 Jan 1.