1969 - 1970年卡尔加里的麻疹疫情；疫苗接种对个人和社区的保护作用。
The measles epidemic in Calgary 1969-70; the protective effect of vaccination for the individual and the community.
作者信息
O'Neil A E
出版信息
Can Med Assoc J. 1971 Oct 23;105(8):819-25.
Abstract
Twenty per cent of the city's population of 375,000 had had live measles vaccination as pre-school children in the preceding four years. Protection rates for killed-live vaccine schedule (Edmonston) and live vaccine only (Schwarz) were approximately 66%, not diminishing in four years; the rates for killed vaccine only (three doses) were similar for 18 months, diminishing later. As the numbers who have acquired immunity by contracting the disease fall by 10 percentage points, numbers immunized by live vaccines must rise by 15 percentage points to maintain an equivalent balance of immune and susceptible subjects.
摘要
该市37.5万人口中，20%在过去四年里曾在学龄前接受过麻疹活疫苗接种。埃德蒙斯顿（Edmonston）灭活-活疫苗接种程序和仅接种施瓦茨（Schwarz）活疫苗的保护率约为66%，四年内没有下降；仅接种灭活疫苗（三剂）的18个月保护率相似，之后下降。随着因感染疾病而获得免疫力的人数下降10个百分点，通过活疫苗免疫的人数必须上升15个百分点，以维持免疫和易感人群的等效平衡。
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