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脑积水性痴呆中的遗忘-虚构综合征及酒精中毒性柯萨科夫精神病。

Amnestic-confabulatory syndrome in hydrocephalic dementia and Korsakoff's psychosis in alcoholism.

作者信息

Berglund M, Gustafson L, Hagberg B

出版信息

Acta Psychiatr Scand. 1979 Oct;60(4):323-33. doi: 10.1111/j.1600-0447.1979.tb00282.x.

Abstract

The clinical course of six alcoholics with Korsakoff's psyter shunt operation. The initial clinical state as well as the symptom improvement showed important similarities between the Korsakoff group and the hydrocephalic dementia group, who improved after shunt operation. Fantastic confabulation and appraxia were only observed in the hydrocephalic dementia group. Psychometrically, both groups showed a similar degree of improvement of the initially impaired verbal memory while only the hydrocephalic dementia group showed impairment of spatial abilities indicating a constructional apraxia. It is suggested that the similarities of the two conditions are related to dysfunction of diencephalic and temporal-limbic structures. The constructional and general apraxia as well as the fantastic confabulation in hydrocephalic dementia indicate a cortical, especially frontal cortical, dysfunction in this disorder.

摘要

6例患有科萨科夫精神病分流手术的酗酒者的临床病程。科萨科夫组与脑积水性痴呆组在初始临床状态以及症状改善方面显示出重要的相似之处,这两组在分流手术后均有改善。离奇的虚构和失用症仅在脑积水性痴呆组中观察到。从心理测量学角度来看,两组在最初受损的言语记忆方面均显示出相似程度的改善,而只有脑积水性痴呆组表现出空间能力受损,提示存在结构性失用症。有人提出,这两种情况的相似性与间脑和颞叶边缘结构的功能障碍有关。脑积水性痴呆中的结构性和一般性失用症以及离奇的虚构表明该疾病存在皮质功能障碍,尤其是额叶皮质功能障碍。

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