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杜兴氏肌营养不良女性携带者的心电图研究。

Electrocardiographic studies in female carriers of Duchenne muscular dystrophy.

作者信息

Lukasik E

出版信息

J Neurol. 1975 Aug 1;209(4):279-85. doi: 10.1007/BF00314367.

DOI:10.1007/BF00314367
PMID:51911
Abstract

The incidence of electrocardiographic features "typical" for the Duchenne progressive muscular dystrophy (PMD) was investigated in 191 carriers: 136 mothers and 55 daughers. The typical PMD pattern was seen in 6.6% of the mothers, and a pattern similar to that observed in PMD in 2.9%. Among daughters of carriers the percentages were 16.4 and 1.8 respectively. The daughters obviously belong to a much lower age bracket (average 13.3 years) and therefore must be followed for the eventual disappearance of the "juvenile" ECG features, which, in this group, may reduce the incidence of the typical PMD electrocardiograms. The need for more thorough clinical appraisal of the myocardium in carriers is emphasized, especially in those with the "typical" PMD electrocardiograms, with the help of hemodynamic investigations.

摘要

对191名杜氏进行性肌营养不良症(PMD)携带者(136名母亲和55名女儿)的心电图特征“典型”情况进行了调查。6.6%的母亲出现典型的PMD模式,2.9%出现与PMD中观察到的模式相似的情况。在携带者的女儿中,这两个百分比分别为16.4%和1.8%。女儿明显属于年龄小得多的年龄段(平均13.3岁),因此必须随访观察“青少年”心电图特征最终是否消失,在该组中,这些特征可能会降低典型PMD心电图的发生率。强调需要对携带者的心肌进行更全面的临床评估,特别是对那些有典型PMD心电图的携带者,借助血流动力学检查。

相似文献

1
Electrocardiographic studies in female carriers of Duchenne muscular dystrophy.杜兴氏肌营养不良女性携带者的心电图研究。
J Neurol. 1975 Aug 1;209(4):279-85. doi: 10.1007/BF00314367.
2
Duchenne pseudohypertrophic muscular dystrophy: a clinical and electrocardiographic study of patients and female carriers.杜兴氏假肥大性肌营养不良症:患者及女性携带者的临床与心电图研究
Aust N Z J Med. 1974 Feb;4(1):41-7. doi: 10.1111/j.1445-5994.1974.tb03144.x.
3
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5
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6
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Clin Chem. 1977 Dec;23(12):2341-3.
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引用本文的文献

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Three cases of manifesting female carriers in patients with Duchenne muscular dystrophy.三例杜氏肌营养不良症患者的表现型女性携带者。
Yonsei Med J. 2011 Jan;52(1):192-5. doi: 10.3349/ymj.2011.52.1.192.
2
A manifesting carrier of Duchenne muscular dystrophy with severe myocardial symptoms.一名患有杜氏肌营养不良症且伴有严重心肌症状的显性携带者。
J Neurol. 1990 Dec;237(8):483-5. doi: 10.1007/BF00314767.

本文引用的文献

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