Salonen J T, Puska P, Mustaniemi H
Br Med J. 1979 Nov 10;2(6199):1178-83. doi: 10.1136/bmj.2.6199.1178.
A comprehensive community programme studying the control of cardiovascular diseases (CVD) was carried out in North Karelia, Finland, between 1972 and 1977. The main objective was to reduce the mortality and morbidity of CVD, particularly in middle-aged men. Changes in the mortality and incidence of CVD were monitored by community-based registers of cases of acute myocardial infarction (AMI) and stroke and data on death certificates. During the programme the total mortality in the area decreased by 5% and the mortality from CVD decreased by 13% among men and 31% among women aged 30-64 years. The incidence of AMI fell by 16% among men and 5% among women, while that of cerebral stroke fell by 38% among men and 50% among women. Changes in mortality in North Karelia were compared with those in a matched control area; the difference between the two areas was not significant. The true effect of the programme cannot be deduced from these results, but mortality from CVD and the incidence of AMI and stroke fell during the five years studied. Thus the changes in mortality and morbidity of CVD accorded with the initial objectives of the programme.
1972年至1977年期间,芬兰北卡累利阿实施了一项研究心血管疾病(CVD)控制的综合社区项目。主要目标是降低心血管疾病的死亡率和发病率,尤其是中年男性的相关指标。通过基于社区的急性心肌梗死(AMI)和中风病例登记以及死亡证明数据,监测心血管疾病死亡率和发病率的变化。在该项目实施期间,该地区的总死亡率下降了5%,30至64岁男性的心血管疾病死亡率下降了13%,女性下降了31%。男性急性心肌梗死发病率下降了16%,女性下降了5%,而男性脑卒中发病率下降了38%,女性下降了50%。将北卡累利阿的死亡率变化与一个匹配的对照地区进行了比较;两个地区之间的差异不显著。该项目的实际效果无法从这些结果中推断出来,但在所研究的五年中,心血管疾病死亡率以及急性心肌梗死和中风的发病率有所下降。因此,心血管疾病死亡率和发病率的变化符合该项目的初始目标。