Prentice B, Robinson B L
Can Med Assoc J. 1979 Sep 22;121(6):745-9.
Six cases of Providencia bacteremia occurring between 1969 and 1978 were reviewed. These cases represented 3% of the gram-negative bacteremias occurring at one hospital. All six cases of Providencia bacteremia were secondary to urinary tract infection with P. stuartii, and in most the infection developed only shortly before the onset of bacteremia; in three cases the bacteremia developed immediately following manipulation of the urinary tract. Patients with long-standing Providencia infections did not acquire bacteremia. The signs and symptoms of Providencia bacteremia were typical of those of septicemia except that vascular collapse was not a prominent feature, occurring in only one patient. The mortality was 33%. All the Providencia strains cultured from the bloodstream were susceptible to gentamicin, although the frequency of gentamicin resistance increased from roughly 10% to 50% during the period studied; the increase in gentamicin use over this period was more gradual. Also noted was a decrease in resistance to ampicillin that paralleled a decrease in ampicillin use. All the Providencia strains were susceptible to amikacin.
对1969年至1978年间发生的6例普罗威登斯菌血症病例进行了回顾。这些病例占某一医院革兰氏阴性菌血症病例的3%。所有6例普罗威登斯菌血症均继发于斯氏普罗威登斯菌引起的尿路感染，且大多数感染仅在菌血症发作前不久发生；3例菌血症在尿路操作后立即发生。长期感染普罗威登斯菌的患者未发生菌血症。普罗威登斯菌血症的体征和症状是败血症的典型表现，但血管虚脱不是突出特征，仅1例患者出现。死亡率为33%。从血液中培养出的所有普罗威登斯菌株对庆大霉素敏感，尽管在研究期间庆大霉素耐药率从约10%逐渐增加到5%；在此期间庆大霉素使用量的增加更为缓慢。还注意到对氨苄西林的耐药性下降与氨苄西林使用量的下降平行。所有普罗威登斯菌株对阿米卡星敏感。
