斯普拉格-道利大鼠的自发性内分泌肿瘤。
Spontaneous endocrine tumors in Sprague-Dawley rats.
作者信息
Suzuki H, Mohr U, Kimmerle G
出版信息
J Cancer Res Clin Oncol. 1979 Oct;95(2):187-96. doi: 10.1007/BF00401012.
Abstract
Spontaneous endocrine tumors were found in 81 of 100 Sprague-Dawley rats (42 males and 39 females) which survived for more than 2 years. Most of these tumors were medullary carcinomas of the thyroid, followed by tumors of the anterior pituitary gland, pheochromocytomas and cortical adenomas of the adrenal gland, and islet cell tumors of the pancreas. Multiple occurrence of these tumors was frequently observed. This study describes the morphology of these spontaneous endocrine tumors.
摘要
在100只存活超过2年的斯普拉格-道利大鼠（42只雄性和39只雌性）中，发现了81例自发性内分泌肿瘤。这些肿瘤大多为甲状腺髓样癌，其次是垂体前叶肿瘤、肾上腺嗜铬细胞瘤和皮质腺瘤，以及胰腺胰岛细胞瘤。经常观察到这些肿瘤的多发性。本研究描述了这些自发性内分泌肿瘤的形态。
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