Wandless I, Mucklow J C, Smith A, Prudham D
J R Coll Gen Pract. 1979 Jul;29(204):391-6.
Compliance with regular medicine taking has been assessed in 81 patients, aged 65 and over, living at home. Interview assessment, home tablet count, and retrospective review of general practice prescription record cards provided three indices of compliance.Deviation by more than 10 per cent from absolute adherence to the prescription was found in 53 per cent of all tablet counts and was significantly more common in women than in men. Errors were also more common when medicines were to be taken more than once daily.The compliance index obtained by inspection of prescription records correlated closely with the index calculated from tablet counts (r(s) = 0.68; p < 0.001) for 129 separate medicines taken regularly. Poor compliance with an individual medicine could be predicted accurately in 66 per cent of cases. A combination of prescription record inspection and interview assessment increased the accuracy of this prediction to 86 per cent.These findings suggest that, using simple methods, the level of compliance can be accurately predicted in a substantial number of elderly patients at home.
对81名65岁及以上居家老人的服药依从性进行了评估。通过访谈评估、家庭药片计数以及回顾全科医疗处方记录卡得出了三个依从性指标。在所有药片计数中，53%的情况与完全按照处方服药的偏差超过10%，且女性比男性更为常见。当药物需要每日服用多次时，错误也更常见。通过检查处方记录获得的依从性指数与根据药片计数计算出的指数密切相关（斯皮尔曼等级相关系数r(s) = 0.68；p < 0.001），涉及129种定期服用的不同药物。在66%的病例中，可以准确预测对某一种药物的依从性差。将处方记录检查和访谈评估相结合，可将这种预测的准确性提高到86%。这些发现表明，使用简单的方法，可以在大量居家老年患者中准确预测依从性水平。
