Parkin D M, Henney C R, Quirk J, Crooks J
Br Med J. 1976 Sep 18;2(6037):686-8. doi: 10.1136/bmj.2.6037.686.
A study of 130 patients discharged from four hospital wards dealing mainly with acute medical cases showed that 66 deviated from the drug regimen prescribed on discharge. Of the patients, 46 did not have a clear understanding of the regimen (non-comprehension) and 20 of the remaining 84 patients understood the prescribed regimen but did not follow the instructions (non-compliance). The prescribing of complex drug regimens, and the availability of medicines prescribed before admission to hospital appeared to be the two main factors influencing non-comprehension and non-compliance.
一项针对130名从四个主要处理急性医疗病例的医院病房出院的患者的研究表明，66名患者偏离了出院时规定的药物治疗方案。在这些患者中，46名对治疗方案没有清晰的理解（理解不足），其余84名患者中有20名理解规定的治疗方案但未遵循医嘱（不依从）。复杂药物治疗方案的开具以及入院前开具的药物的可得性似乎是影响理解不足和不依从的两个主要因素。
