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The synthesis of homocystine, cystathionine, and cystine by cultured diploid and heteroploid human cells.

作者信息

Eagle H, Washington C, Friedman S M

出版信息

Proc Natl Acad Sci U S A. 1966 Jul;56(1):156-63. doi: 10.1073/pnas.56.1.156.

DOI:10.1073/pnas.56.1.156
PMID:5229844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC285689/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e9/285689/0e72bc945c6e/pnas00146-0176-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e9/285689/22c0fb95d0dc/pnas00146-0176-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e9/285689/8fa84eb2ed80/pnas00146-0176-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e9/285689/0da5c10ee175/pnas00146-0176-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e9/285689/0e72bc945c6e/pnas00146-0176-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e9/285689/22c0fb95d0dc/pnas00146-0176-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e9/285689/8fa84eb2ed80/pnas00146-0176-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e9/285689/0da5c10ee175/pnas00146-0176-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86e9/285689/0e72bc945c6e/pnas00146-0176-d.jpg

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The synthesis of homocystine, cystathionine, and cystine by cultured diploid and heteroploid human cells.培养的二倍体和异倍体人类细胞对高胱氨酸、胱硫醚和胱氨酸的合成。
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本文引用的文献

1
The desoxyribose nucleic acid content of animal nuclei.动物细胞核中的脱氧核糖核酸含量。
Physiol Zool. 1950 Jul;23(3):169-98. doi: 10.1086/physzool.23.3.30152074.
2
Cystathioniuria.胱硫醚尿症
Ann Hum Genet. 1959 Dec;23:442-53. doi: 10.1111/j.1469-1809.1959.tb01485.x.
3
THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS.人二倍体细胞株的体外寿命有限。
芳香烃受体（AhR）的激活导致肠道微生物组发生改变，并以 CXCR2 依赖的方式影响髓源性抑制细胞的诱导。
Int J Mol Sci. 2020 Dec 17;21(24):9613. doi: 10.3390/ijms21249613.
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Targeting extracellular nutrient dependencies of cancer cells.针对癌细胞的细胞外营养依赖性。
Mol Metab. 2020 Mar;33:67-82. doi: 10.1016/j.molmet.2019.11.011. Epub 2019 Nov 23.
5
Immunometabolism: A new target for improving cancer immunotherapy.免疫代谢：改善癌症免疫疗法的新靶点。
Adv Cancer Res. 2019;143:195-253. doi: 10.1016/bs.acr.2019.03.004. Epub 2019 Apr 17.
6
K-Ras Activation Induces Differential Sensitivity to Sulfur Amino Acid Limitation and Deprivation and to Oxidative and Anti-Oxidative Stress in Mouse Fibroblasts.K-Ras激活诱导小鼠成纤维细胞对硫氨基酸限制与剥夺以及氧化和抗氧化应激产生不同敏感性。
PLoS One. 2016 Sep 29;11(9):e0163790. doi: 10.1371/journal.pone.0163790. eCollection 2016.
7
Disruption of GRM1-mediated signalling using riluzole results in DNA damage in melanoma cells.使用利鲁唑破坏 GRM1 介导的信号转导可导致黑素瘤细胞中的 DNA 损伤。
Pigment Cell Melanoma Res. 2014 Mar;27(2):263-74. doi: 10.1111/pcmr.12207. Epub 2014 Jan 22.
8
Amino acid and vitamin requirements in mammalian cultured cells.哺乳动物培养细胞的氨基酸和维生素需求。
Amino Acids. 1993 Feb;5(1):1-16. doi: 10.1007/BF00806187.
9
Myeloid-derived suppressor cells and anti-tumor T cells: a complex relationship.髓系来源的抑制细胞与抗肿瘤 T 细胞：复杂的关系。
Immunol Invest. 2012;41(6-7):595-613. doi: 10.3109/08820139.2012.673191.
10
Activated human CD4+ T cells express transporters for both cysteine and cystine.活化的人 CD4+ T 细胞表达半胱氨酸和胱氨酸的转运蛋白。
Sci Rep. 2012;2:266. doi: 10.1038/srep00266. Epub 2012 Feb 14.
Exp Cell Res. 1965 Mar;37:614-36. doi: 10.1016/0014-4827(65)90211-9.
4
CONTACT INHIBITION, MACROMOLECULAR SYNTHESIS, AND POLYRIBOSOMES IN CULTURED HUMAN DIPLOID FIBROBLASTS.培养的人二倍体成纤维细胞中的接触抑制、大分子合成与多核糖体
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Cold Spring Harb Symp Quant Biol. 1964;29:223-31. doi: 10.1101/sqb.1964.029.01.026.
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METABOLIC CONTROLS IN CULTURED MAMMALIAN CELLS.培养的哺乳动物细胞中的代谢调控
Science. 1965 Apr 2;148(3666):42-51. doi: 10.1126/science.148.3666.42.
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STUDIES OF A HUMAN TUMOR CELL LINE WITH A DIPLOID KARYOTYPE.对具有二倍体核型的人类肿瘤细胞系的研究。
Cancer. 1964 Feb;17:170-5. doi: 10.1002/1097-0142(196402)17:2<170::aid-cncr2820170206>3.0.co;2-n.
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LONG-TERM CULTIVATION OF HYPODIPLOID HUMAN TUMOR CELLS.亚二倍体人类肿瘤细胞的长期培养
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9
Cystathioninuria.
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10
Continuous scintillation counting of carbon-14 and tritium in effluent of the automatic amino acid analyzer.自动氨基酸分析仪流出物中碳-14和氚的连续闪烁计数
Anal Biochem. 1962 Dec;4:444-58. doi: 10.1016/0003-2697(62)90126-4.