Ossenkopp K P, Sanberg P R
Physiol Behav. 1979 Nov;23(5):809-12. doi: 10.1016/0031-9384(79)90182-3.
Repeated low-intensity electrical stimulation (kindling) of the amygdala eventually produces convulsive behavior in animals. The present study examined the relationship between behaviors displayed in a novel open-field situation with behavioral characteristics of the kindled clonic convulsion (CC). Wistar rats were given two open-field tests and were subsequently kindled to clonic convulsions. A multiple regression analysis indicated that rats which urinated more often in the open-field tests tended to show longer latencies to CC onset. Thus, open-field urination was a significant predictor of latency to CC onset. It is suggested that an emotionality construct may be related to rate of kindling.
反复对杏仁核进行低强度电刺激（点燃）最终会在动物身上引发惊厥行为。本研究考察了在新奇旷场情境中表现出的行为与点燃性阵挛性惊厥（CC）行为特征之间的关系。对Wistar大鼠进行了两次旷场试验，随后将其点燃至阵挛性惊厥。多元回归分析表明，在旷场试验中排尿更频繁的大鼠往往出现CC发作的潜伏期更长。因此，旷场排尿是CC发作潜伏期的一个重要预测指标。提示情绪性结构可能与点燃率有关。
