Heath D D, Lawrence S B, Yong W K
Res Vet Sci. 1979 Sep;27(2):210-2.
Lambs were infected orally at 14 weeks of age with either Taenia hydatigena, T ovis or Echinococcus granulosus eggs. To induce high levels of resistance to oral reinfection, they were then injected intramuscularly with eggs of the homologous species four weeks and eight weeks later. The degree of immunity was then tested by oral challenge with eggs from either the homologous or an heterologous species. Autopsy results indicated that prior infection with an homologous species induced a very high degree of immunity to challenge infection. Prior infection with all combinations of heterologous species resulted in a lesser degree of immunity, which appeared to have acted on the establishment phase of development and did not influence cyst survival.
在14周龄时给羔羊经口感染泡状带绦虫、羊绦虫或细粒棘球绦虫虫卵。为诱导对再次经口感染产生高水平抵抗力，在4周和8周后给它们肌肉注射同源物种的虫卵。然后通过用同源或异源物种的虫卵经口攻毒来测试免疫程度。尸检结果表明，先前感染同源物种可诱导对攻击感染产生非常高的免疫程度。先前感染所有异源物种组合均导致较低程度的免疫，这似乎作用于发育的建立阶段，并且不影响囊肿存活。
