Doxycycline prophylaxis in fracture surgery.

Doxycycline was given as preventive preoperative treatment to 64 patients with fractured collum femoris. 46 patients, not administered doxycycline, served as controls. The overall incidence of postoperative infection was 6.3 and 6.5% in treated and control groups respectively. It is concluded that doxycycline preventive treatment offers no advantage in this type of operative procedure.