Garraway W M, Whisnant J P, Kurland L T, O'Fallon W M
Stroke. 1979 Nov-Dec;10(6):657-63. doi: 10.1161/01.str.10.6.657.
This study has identified all persons in the population of Rochester, Minnesota, who had a diagnosis of cerebral infarction during the period Jan. 1, 1970, through Dec. 31, 1974, and has confirmed the continuing decline in the incidence rate previously reported. The decline in the rate has been accelerating, with a relatively greater reduction occurring in women and in the more elderly age groups. There has been a decline in the prevalence rate in women which was not seen in men. The over-all impact of cerebral infarction was to reduce the proportion of those persons who were completely independent from 57% before cerebral infarction to 16% after infarction. Comparison of survival among patients with cerebral infarction occurring in the two quinquennia 1945--49 and 1970--74 showed only a 2% increased probability of survival at 30 days; the difference in survival increased progressively to 16% at 5 years. The reason for the declining incidence and increased survival in cerebral infarction in this population has not been established, but evidence of increased community surveillance and treatment of hypertension among persons before the onset of cerebral infarction is presented.
本研究已确定了明尼苏达州罗切斯特市在1970年1月1日至1974年12月31日期间被诊断为脑梗死的所有人员，并证实了此前报道的发病率持续下降。发病率的下降一直在加速，女性和年龄较大的年龄组下降幅度相对更大。女性的患病率有所下降，而男性则未出现这种情况。脑梗死的总体影响是，完全独立的人群比例从脑梗死前的57%降至梗死后的16%。对1945 - 1949年和1970 - 1974年这两个五年期发生脑梗死的患者的生存率进行比较，结果显示30天时的生存概率仅增加了2%；5年时生存差异逐渐增至16%。该人群中脑梗死发病率下降和生存率提高的原因尚未明确，但有证据表明在脑梗死发病前对人群进行了更多的社区监测和高血压治疗。
