Booz K, Faulhauer K, Donauer E, Nieland F
Z Mikrosk Anat Forsch. 1979;93(4):643-61.
40 adult cats were made hydrocephalic by intracisternal injection of 200 mg Kaolin. 34 survived between 24 hours to 4 months. In 19 cases a ventriculostomy was carried out, whereby in 13 animals a contrast filling of the central canal occurred. The contrast medium injected into the ventricles entered the external CSF-space in the lumbo-sacral junction of the filum terminale. Light- and electron-microscopic studies showed adaptive structural changes of the central canal epithelium in the early stages. In later stages massive destructions of ependyma and spinal cord parenchyma were found.
通过脑池内注射200毫克高岭土使40只成年猫发生脑积水。34只存活24小时至4个月。19例进行了脑室造口术,其中13只动物中央管出现造影剂充盈。注入脑室内的造影剂进入终丝腰骶交界处的外部脑脊液间隙。光镜和电镜研究显示早期中央管上皮有适应性结构变化。后期发现室管膜和脊髓实质大量破坏。