Rönnbäck C
Acta Radiol Oncol Radiat Phys Biol. 1979;18(3):225-34. doi: 10.3109/02841867909128210.
Pregnant CBA-mice were injected with 3.7 x 10(5) Bq (10 muCi) 90Sr on the 8th, 11th, 13th, 16th or 19th day post coitum. The effect on the ovaries in the intrauterine-treated animals was analysed on the 28th, 56th and 84th day post partum. The result was expressed as a comparison between the number of cells in different stages of development in the treated individuals compared to untreated control animals. The reduction of the number of cells in the ovaries was strongly correlated to the time of administration of the nuclide with a more increased effect the later during foetal development the contamination occurred. The oocytes and primordial follicles were the most radiation sensitive stages. The remaining cells in the ovaries are supposed to form a numerically reduced pool of functionally normal cells.
在交配后的第8、11、13、16或19天，给怀孕的CBA小鼠注射3.7×10(5) 贝可勒尔（10微居里）的90锶。在产后第28、56和84天分析子宫内接受处理的动物的卵巢所受影响。结果表示为与未处理的对照动物相比，处理个体中不同发育阶段细胞数量的比较。卵巢中细胞数量的减少与核素给药时间密切相关，胎儿发育后期发生污染时影响更大。卵母细胞和原始卵泡是最对辐射敏感的阶段。卵巢中剩余的细胞被认为形成了数量减少的功能正常细胞库。
