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与内部沉积相比,长期外部伽马辐射对胎儿卵巢的影响。

Effects on foetal ovaries after protracted, external gamma irradiation as compared with those from internal depositions.

作者信息

Rönnbäck C

出版信息

Acta Radiol Oncol. 1983;22(6):465-71. doi: 10.3109/02841868309135972.

DOI:10.3109/02841868309135972
PMID:6328878
Abstract

Effects of low doses of protracted gamma irradiation on pre- and neonatally exposed ovaries in CBA mice have been compared with those previously obtained by 90Sr contamination of the dam. The total number of germ cells at 56 days of age was reduced to about 50 per cent after a dose of 0.09 Gy given during four days from the 19th day post coitum to the 2nd day post partum. The highest dose level used (0.91 Gy) reduced the frequency to about 10 per cent. Females exposed to the same dose levels at an age of 85 to 90 days showed a lesser degree of injury. The reproductive capacity in females exposed around their birth (expressed as the number of litters per female) was negatively correlated to the dose of gamma irradiation. The effects on the foetal ovaries of 2 to 5 kBq 90Sr given to the dam on the 19th day of gestation seemed to correspond to those from 0.01 Gy from 137Cs under the present circumstances.

摘要

已将低剂量长期伽马辐射对CBA小鼠产前和新生期暴露卵巢的影响,与先前通过母体受90锶污染所获得的影响进行了比较。从交配后第19天到产后第2天,在四天内给予0.09戈瑞的剂量后,56日龄时生殖细胞的总数减少到约50%。所使用的最高剂量水平(0.91戈瑞)使该频率降低到约10%。在85至90日龄时暴露于相同剂量水平的雌性,损伤程度较小。出生前后暴露的雌性的生殖能力(以每只雌性的产仔数表示)与伽马辐射剂量呈负相关。在妊娠第19天给予母体2至5千贝克勒尔90锶对胎儿卵巢的影响,在当前情况下似乎与来自137铯的0.01戈瑞的影响相当。

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Effects on foetal ovaries after protracted, external gamma irradiation as compared with those from internal depositions.与内部沉积相比,长期外部伽马辐射对胎儿卵巢的影响。
Acta Radiol Oncol. 1983;22(6):465-71. doi: 10.3109/02841868309135972.
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