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受90锶污染的牛奶对胎鼠和幼鼠卵巢的影响。

Influence of 90Sr-contaminated milk on the ovaries of foetal and young mice.

作者信息

Rönnbäck C

出版信息

Acta Radiol Oncol. 1981;20(2):131-5. doi: 10.3109/02841868109130433.

DOI:10.3109/02841868109130433
PMID:6270965
Abstract

A dose of 185 kBq (5 microCi) 90Sr was intravenously injected into pregnant CBA-mice on the 19th day post coitum. Four groups of female young were examined when aged 56 days: (1) non-contaminated females (controls), (2) only exposed in utero, (3) only having suckled contaminated milk and (4) exposed to 90Sr in utero and having suckled contaminated milk. The effect of the nuclide was expressed as a comparison of the number of remaining cells in the ovaries, totally and in different stages of development, between 90Sr-contaminated young and controls. Young mice that suckled contaminated milk had a reduced number of cells compared with the controls. The ovaries of in utero contaminated females were injured to a less severe degree if the individuals were given noncontaminated milk, compared with those suckling contaminated dams. Minute changes of the body burden of 90Sr were especially reflected in the number of young oocytes, being the most radiation sensitive stage during the ovarian development.

摘要

在交配后第19天,给怀孕的CBA小鼠静脉注射185千贝可(5微居里)的90锶。当雌性幼鼠56日龄时,对四组进行了检查:(1)未受污染的雌性(对照组),(2)仅在子宫内暴露,(3)仅吸食受污染的乳汁,(4)在子宫内暴露并吸食受污染的乳汁。该核素的影响通过比较90锶污染的幼鼠与对照组卵巢中剩余细胞的总数以及不同发育阶段的细胞数量来表示。吸食受污染乳汁的幼鼠细胞数量比对照组减少。与吸食受污染母鼠乳汁的个体相比,如果给子宫内受污染的雌性提供未受污染的乳汁,其卵巢损伤程度较轻。90锶体内负荷的微小变化尤其反映在初级卵母细胞数量上,初级卵母细胞是卵巢发育过程中对辐射最敏感的阶段。

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Influence of 90Sr-contaminated milk on the ovaries of foetal and young mice.受90锶污染的牛奶对胎鼠和幼鼠卵巢的影响。
Acta Radiol Oncol. 1981;20(2):131-5. doi: 10.3109/02841868109130433.
2
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