Manos J P, Jacobs P F
Antimicrob Agents Chemother. 1979 Nov;16(5):631-4. doi: 10.1128/AAC.16.5.631.
A radiometric assay for gentamicin was compared with an established radioimmunoassay protocol. The coefficients of variation for within-run, day-to-day, and overall runs were consistently higher for the radiometric method as compared with the radioimmunoassay. The coefficient of correlation for 84 patient sera tested by the two methods for gentamicin levels was 0.82. Though less precise, the radiometric method was felt to be an acceptable means of determining gentamicin levels in laboratories where the radioimmunoassay is unavailable.
将庆大霉素的放射测定法与既定的放射免疫测定方案进行了比较。与放射免疫测定法相比,放射测定法在批内、日间和总体测定中的变异系数始终较高。两种方法检测84份患者血清庆大霉素水平的相关系数为0.82。尽管不够精确,但在没有放射免疫测定法的实验室中,放射测定法被认为是测定庆大霉素水平的一种可接受的方法。