Tiffany J M, Blough H A
Proc Natl Acad Sci U S A. 1970 Apr;65(4):1105-12. doi: 10.1073/pnas.65.4.1105.
Possible models of the structure of the influenza virus envelope are considered in terms of the known chemical composition. Models incorporating lipid in the form of a bimolecular leaflet are shown to be unlikely on geometrical grounds. A model having "inverted toadstool" protein units separated by spherical lipid micelles is favored, and is capable of explaining the appearance of the virus in the electron microscope and differences between normal and incomplete (von Magnus) forms of the virus.
根据已知的化学成分,对流感病毒包膜结构的可能模型进行了探讨。从几何学角度来看,包含双分子层脂质形式的模型不太可能成立。一种具有由球形脂质微团隔开的“倒蘑菇”状蛋白质单元的模型更受青睐,它能够解释病毒在电子显微镜下的外观以及病毒正常形式与不完全(冯·马格努斯)形式之间的差异。