关于红细胞膜中脂质与蛋白质的相互作用
On the interactions of lipids and proteins in the red blood cell membrane.
作者信息
Glaser M, Simpkins H, Singer S J, Sheetz M, Chan S I
出版信息
Proc Natl Acad Sci U S A. 1970 Mar;65(3):721-8. doi: 10.1073/pnas.65.3.721.
Abstract
The effects of temperature and of the action of a purified phospholipase C enzyme preparation on human red blood cell membranes has been investigated by chemical analyses, circular dichroism, and proton magnetic resonance measurements. The results indicate that a substantial fraction of the phospholipids and the proteins of the membranes can change structure independently of one another, suggesting a mosaic pattern for the organization of the lipids and proteins in membranes.
摘要
通过化学分析、圆二色性和质子磁共振测量，研究了温度和纯化的磷脂酶C酶制剂对人红细胞膜的作用。结果表明，膜中的很大一部分磷脂和蛋白质可以彼此独立地改变结构，这表明膜中脂质和蛋白质的组织呈现镶嵌模式。
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