Obiaya M O, Haddock D R
Can Anaesth Soc J. 1979 Nov;26(6):496-501. doi: 10.1007/BF03006165.
This study was undertaken to determine the cardiac response of Nigerian hypertensives to anaesthesia and surgery, using systolic time intervals as an indication of ventricular function. Nine hypertensive and eight normotensive patients who were admitted for various operations had carotidogram, phonocardiogram and electrocardiogram recorded simultaneously before induction of anaesthesia, after induction and during operation. The pre-ejection phase, (PEP) and the left ventricular ejection time (LVET) were measured from the tracings and the ratio PEP/LVET was calculated. The results showed that for both normotensive patients and hypertensive patients there was a mean increase of the PEP/LVET ratio under anaesthesia and surgery, indicating deterioration of ventricular function. Hypertensive patients showed a much greater deviation from normal, approaching heart failure values. It is concluded that hypertensive patients seemed to be at greater risk during anaesthesia and surgery. The implication is that hypertensive patients should be adequately treated before operation.
本研究旨在利用收缩期时间间期作为心室功能的指标，确定尼日利亚高血压患者对麻醉和手术的心脏反应。九名因各种手术入院的高血压患者和八名血压正常的患者，在麻醉诱导前、诱导后及手术期间同时记录了颈动脉图、心音图和心电图。从记录中测量射血前期（PEP）和左心室射血时间（LVET），并计算PEP/LVET比值。结果表明，无论是血压正常的患者还是高血压患者，在麻醉和手术期间PEP/LVET比值均有平均升高，表明心室功能恶化。高血压患者与正常情况的偏差更大，接近心力衰竭值。得出的结论是，高血压患者在麻醉和手术期间似乎面临更大风险。这意味着高血压患者在手术前应得到充分治疗。
