Barnard W M, Arden G B
Child Care Health Dev. 1979 Nov-Dec;5(6):421-30. doi: 10.1111/j.1365-2214.1979.tb00148.x.
The VER was studied in normal children aged 4--11 years and in 71 amblyopic children at Moorfields Eye Hospital. Changes in the VER in amblyopia are best observed with 20% contrast and small square sizes. The better eye of untreated amblyopia has a normal time-to-peak for P1 of the cortical response, while that of the amblyopic eye is delayed, the more so with poor binocular vision in partial agreement with our previous findings. We found with a high degree of significance that occlusion therapy renders the VER from the amblyopic eye more 'normal' but causes considerable delay in the VER from the covered eye, even though its visual acuity does not change. At the end of occlusion, these changes are usually reversible although not always completely in patients who have had prolonged occlusion.
对4至11岁的正常儿童以及 Moorfields眼科医院的71名弱视儿童进行了视觉诱发电位（VER）研究。在弱视情况下，使用20%的对比度和小方块尺寸能最好地观察到VER的变化。未经治疗的弱视患者较好的眼睛，其皮层反应P1的峰值时间正常，而弱视眼的峰值时间延迟，双眼视力较差时更是如此，这部分与我们之前的研究结果一致。我们发现，高度显著的是，遮盖疗法使弱视眼的VER更“正常”，但会导致被遮盖眼的VER出现相当大的延迟，即使其视力没有变化。在遮盖结束时，这些变化通常是可逆的，尽管在长期接受遮盖治疗的患者中并不总是完全可逆。
