Arden G B, Barnard W M
Trans Ophthalmol Soc U K (1962). 1979;99(3):419-26.
Average normal values for the VER were obtained in children aged 4 to 11 years. There are slight but significant differences between the values obtained and those found in adults (an increase in the time to peak of P1). In amblyopic eyes the time to peak is increased, and the amplitude reduced, roughly in proportion to the loss of visual acuity and binocularity. The VER is normal in the better eyes of children who have never been treated by occlusion therapy. Occlusion increases the time to peak of the VER, both in serial studies on individuals, and in lateral population studies, so that the response of the better eye is delayed beyond that of the amblyopic eye. After the end of occlusion, the VER change usually returns to normal. In a subgroup of patients with prolonged occlusion, the changes had not completely reversed one year later. In children in whom occlusion therapy had improved visual acuity, the VER returned towards normal.
视觉诱发电位(VER)的平均正常值是在4至11岁的儿童中获得的。所获得的值与成人的值之间存在轻微但显著的差异(P1波峰时间增加)。在弱视眼中,波峰时间增加,波幅降低,大致与视力和双眼视功能丧失程度成比例。从未接受过遮盖疗法治疗的儿童的较好眼的VER是正常的。无论是在个体的系列研究中还是在横向人群研究中,遮盖都会增加VER的波峰时间,以至于较好眼的反应延迟超过弱视眼。遮盖结束后,VER变化通常会恢复正常。在一组遮盖时间延长的患者中,一年后这些变化并未完全逆转。在遮盖疗法提高了视力的儿童中,VER趋向于恢复正常。