Rahn R O, Battista M D, Landry L C
Proc Natl Acad Sci U S A. 1970 Nov;67(3):1390-7. doi: 10.1073/pnas.67.3.1390.
Partial mercuration of DNA, such that roughly one mercuric ion is bound for every two thymine residues, results in an enhancement of the phosphorescence by a factor of ten and a small enhancement of the photosteady thymine dimer yield. Complete mercuration of DNA [one Hg(II) added per momoner unit] results in quenching of the phosphorescence intensity and an inhibition of thymine dimer production. The enhancement of the phosphorescence is interpreted in terms of a heavy-atom effect caused by the preferential binding of Hg(II) to the thymine residues. The quenching of both the thymine phosphorescence and the rate of thymine dimerization upon complete mercuration is probably due to energy transfer from thymine to another base, presumably adenine, which when mercurated acts as an energy trap.
使DNA部分汞化，即每两个胸腺嘧啶残基结合大约一个汞离子，会使磷光增强10倍，并使光稳态下胸腺嘧啶二聚体的产量略有增加。DNA完全汞化（每个单体单元添加一个Hg(II)）会导致磷光强度猝灭并抑制胸腺嘧啶二聚体的产生。磷光的增强被解释为Hg(II)优先结合到胸腺嘧啶残基上所引起的重原子效应。完全汞化时胸腺嘧啶磷光和胸腺嘧啶二聚化速率的猝灭可能是由于能量从胸腺嘧啶转移到另一种碱基，推测是腺嘌呤，腺嘌呤汞化后充当能量陷阱。
