顺二氯双（异丙胺）反二羟基铂（IV）（CHIP）对中国仓鼠和C3H小鼠肿瘤细胞的作用机制及其与X射线照射的相互作用。 - Suppr | 超能文献

The mechanism of action of cis-dichloro-bis (isopropylamine) trans dihydroxyplatinum IV (CHIP) on Chinese hamster and C3H mouse tumor cells and its interaction with X-irradiation.

作者信息

Nias A H, Bocian E, Laverick M

出版信息

Int J Radiat Oncol Biol Phys. 1979 Aug;5(8):1341-4. doi: 10.1016/0360-3016(79)90666-7.

DOI:10.1016/0360-3016(79)90666-7

Abstract

摘要

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The mode of action of cis dichloro-bis (isopropylamine) trans dihydroxy platinum IV (CHIP) studied by the analysis of chromosome aberration production.通过分析染色体畸变产生来研究顺二氯双（异丙胺）反二羟基铂（IV）（CHIP）的作用方式。

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Sister chromatid exchanges induced by two radiosensitizing platinum compounds (cis-dichloro-bis isopropylamine trans dihydroxy platinum IV (CHIP) and cis platinum metronidazole2Cl2(FLAP)) in CHO cells in vitro.两种放射增敏铂化合物（顺式二氯双异丙胺反式二羟基铂IV（CHIP）和顺铂甲硝唑2Cl2（FLAP））在体外诱导CHO细胞中的姐妹染色单体交换。

Br J Cancer. 1983 Dec;48(6):803-7. doi: 10.1038/bjc.1983.270.