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Mechanism of hepatic drug oxidation and its relationship to individual differences in rates of oxidation in man.

作者信息

Davies D S, Thorgeirsson S S

出版信息

Ann N Y Acad Sci. 1971 Jul 6;179:411-20. doi: 10.1111/j.1749-6632.1971.tb46918.x.

DOI:10.1111/j.1749-6632.1971.tb46918.x
PMID:5285386
Abstract
摘要

相似文献

1
Mechanism of hepatic drug oxidation and its relationship to individual differences in rates of oxidation in man.肝脏药物氧化机制及其与人氧化速率个体差异的关系。
Ann N Y Acad Sci. 1971 Jul 6;179:411-20. doi: 10.1111/j.1749-6632.1971.tb46918.x.
2
Genetic control of drug levels and of the induction of drug-metabolizing enzymes in man: individual variability in the extent of allopurinol and nortriptyline inhibition of drug metabolism.人体中药物水平及药物代谢酶诱导的遗传控制：别嘌醇和去甲替林对药物代谢抑制程度的个体差异
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3
Interindividual differences in rates of drug oxidation in man.人类药物氧化速率的个体差异。
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Effects of phenylbutazone on liver microsomal demethylase.保泰松对肝脏微粒体脱甲基酶的影响。
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5
Effect of oral contraceptives on drug metabolism.口服避孕药对药物代谢的影响。
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6
Factors affecting drug metabolism.影响药物代谢的因素。
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Relationship between plasma antipyrine half-lives and hepatic microsomal drug metabolism in dogs.
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Effect of temperature on the relationship between hepatic microsomal cytochrome P-450 reduction and ethylmorphine demethylation.
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Kinetic studies of the N-demethylation of ethylmorphine by a cytochrome P-450-dependent enzyme system in human liver microsomes.人肝微粒体中细胞色素P-450依赖酶系统对乙基吗啡N-去甲基化的动力学研究。
Biochem J. 1971 Mar;122(1):30P. doi: 10.1042/bj1220030pa.
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Impairment of human drug metabolism by oral contraceptive steroids.口服避孕类固醇对人体药物代谢的损害。
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Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big Data.使用抗氧化反应元件报告基因检测模型和大数据对氧化应激引起的肝毒性进行机制剖析
Environ Health Perspect. 2016 May;124(5):634-41. doi: 10.1289/ehp.1509763. Epub 2015 Sep 18.
2
Influence of liver disease and environmental factors on hepatic monooxygenase activity in vitro.肝脏疾病和环境因素对体外肝单加氧酶活性的影响。
Eur J Clin Pharmacol. 1981;20(1):39-46. doi: 10.1007/BF00554665.
3
The effect of malnutrition on the pharmacokinetics of phenylbutazone.
营养不良对保泰松药代动力学的影响。
Clin Pharmacokinet. 1981 Mar-Apr;6(2):152-9. doi: 10.2165/00003088-198106020-00005.
4
Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.人肝脏针吸活检标本微粒体组分中的单加氧酶活性
Br J Clin Pharmacol. 1980 Jan;9(1):11-9. doi: 10.1111/j.1365-2125.1980.tb04790.x.
5
Immediate decrease by hydrocortisone of the plasma half-life of antipyrine.氢化可的松使安替比林的血浆半衰期立即缩短。
Br J Pharmacol. 1973 Feb;47(2):434-6. doi: 10.1111/j.1476-5381.1973.tb08344.x.
6
[Studies on the effect of uremia on phenylbutazone and aminophenazone metabolism in man].
Klin Wochenschr. 1972 Dec 1;50(23):1092-6. doi: 10.1007/BF01486853.
7
The pharmacokinetics of acetanilide and of diphenylhydantoin sodium.乙酰苯胺和苯妥英钠的药代动力学。
Eur J Clin Pharmacol. 1974 Oct 4;7(6):461-6. doi: 10.1007/BF00560359.
8
Acetanilide oxidation in phenylbutazone-associated hypoplastic anaemia.保泰松相关的再生障碍性贫血中乙酰苯胺氧化作用
Br Med J. 1974 Aug 3;3(5926):313-7. doi: 10.1136/bmj.3.5926.313.
9
Assessment of liver ability to biotransformation of antipyrine in uraemic patients on regular peritoneal dialysis treatment.
Int Urol Nephrol. 1989;21(5):541-5. doi: 10.1007/BF02549593.
10
Altered elimination of antipyrine in patients with acute viral hepatitis.急性病毒性肝炎患者安替比林消除情况的改变。
Gut. 1976 May;17(5):341-4. doi: 10.1136/gut.17.5.341.